HLA Typing in Uganda

White blood cells contain a protein called human leukocyte antigen (HLA). They are essential in the body’s defense against bacterial or viral infections and control how it reacts to medications, vaccines, autoimmune diseases, and malignancies. Accepting or rejecting a transplanted organ or bone marrow is also based on HLA types. The HLA Typing cost in Uganda starts from $230. Uganda offers HLA Typing testing services in Mobile Van clinics as part of a government initiative to complete as many HLA Typing tests as possible. This makes it simple and quick for the Ugandan Hospital to locate matches for HLA typing.

HLA Typing Cost in Uganda

HLA Typing Cost in Uganda – Bone Marrow Transplants

A method known as HLA typing is used to identify antigens, in particular white blood cells. With these cell markers, the organism’s immune system can distinguish between self and non-self. The HLA Typing cost in Uganda is around $360 for a Bone Marrow Transplant. If no match exists within the family, stem cell databases worldwide are examined. Millions of people who offered to donate stem cells to someone needing a stem cell transplant have left their HLA information in these registries. The match is said to be good when HLA typing and 5 or 6 molecules match.

HLA Typing Cost in Uganda – Kidney Transplants

Human leukocyte antigen (HLA) complex testing is done in laboratories on candidate and organ donor tissues to determine the compatibility of transplants. The HLA typing process is another name for it. There is a lower chance that the candidate’s body will reject the transplant when the candidate and donor are more compatible. The HLA Typing Cost in Uganda is around $310 for Kidney Transplant.

High-Resolution HLA Typing cost in Uganda

When performing an organ transplant, the HLA Typing High-Resolution test matches bone marrow, cord blood, or any other organ. The gene family that includes HLA (Human Leukocyte Antigen) is crucial for immunological responses. Both donor and receiver samples are used in the test. A group of alleles that encode the identical protein sequence for the area of the HLA molecule known as the antigen binding site and exclude alleles that are not produced as cell-surface proteins is referred to as a high-resolution typing result. The cost of High-Resolution HLA Typing in Uganda is around $600.

HLA Typing Cost in Uganda

Why are HLA typing tests required?

Because different individuals may have extremely different HLA Typing, which may create alloreactivity between recipients and donors, laboratory testing for HLA is routinely performed to establish transplant compatibility.

HLA Typing tests may be used in pharmacogenetics to determine the risk of an adverse reaction to specific medications, to examine disease associations in vaccination trials, or for platelet transfusion assistance, in addition to its involvement in transplantation. The majority of HLA testing is now done utilizing molecular genetic approaches.

Donor Registries

A donor registry collects donor information from those willing and able to donate bone marrow or other organs. People from all across the world register with various HLA Donor Registries. When a patient needs a bone marrow transplant or organ transplantation, the HLA Typing of the patient is matched with the closest match from the donor registry. Uganda has its donor database. Additionally, they also source and find donors from international registries. A few of the famous registries are:

• DKMS
• Be The Match
• DATRI
• WMDA

Importance of Matched HLA Typing

The degree to which the patient’s HLA type and the donor’s HLA type match is crucial. The quantity of HLA molecules that any two individuals share is known as the HLA “match.” Ten HLA molecules are typically used in HLA matching. The better the match, the more molecules two people have in common. Consequently, they are less likely to launch an attack since their immune systems are less likely to perceive one another as “foreign.”

What is the HLA Typing accuracy rate in Uganda?

The Ugandan Clinics and HLA Typing test centers are well equipped with high-quality technologies and the latest machines, which help them provide a highly accurate HLA Typing result. If the HLA Typing result is correct and the match is found, the transplant will be highly successful without any complication of rejection. The accuracy rate of the HLA Typing Test in Uganda is more than 95%.

HLA Typing Centers in Uganda

The HLA Typing Test Centers in Uganga have the latest technologies, and hematologists are well-experienced and provide HLA Typing results with complete accuracy. The quality of labs in Uganda is excellent; they are maintained, and the staff in the centers provide high-quality services to the patients. The results of HLA Typing are provided in a timely, within 13-15 days, which helps find a match and get a transplant done in no time.

Insurance Coverage for HLA Typing in Uganda

The government in Uganda does not provide Insurance coverage for the HLA Typing test and finding matches. But the Insurance is offered to bear the cost of transplant surgeries after finding a matched donor. Many famous insurance companies cover Bone marrow transplants, Liver transplants, and Kidney transplants. As Uganda’s HLA Typing cost is not much affordable, insurance coverage is not required.

FAQs on HLA Typing in Uganda